Seroprevalence of Hepatitis B Virus Surface Antigen (HBsAg) Positivity in KAHS Teaching Hospital, Jumla

Authors

  • Bibek Pun Magar Lecturer, Department of biochemistry, Karnali Academy of Health Sciences, Jumla
  • Niresh Thapa Associate Professor, Department of Emergency Medicine and General Practices, Karnali Academy of Health Sciences, Jumla
  • Elisha Rana Nursing Officer, Karnali Academy of Health Sciences, Jumla
  • Keshav Raj Joshi Laboratory Scientific Officer, Krown Laboratory, Kathmandu, Nepal
  • Arjun Prasad Tiwari Medical Officer, Department of Anesthesiology and Critical Care, KAHS, Jumla

Keywords:

Seroprevalence, Rural area, High-risk group, Hepatitis B virus, HBsAg infectionRural area

Abstract

Background: Hepatitis B Virus (HBV) infection is a foremost global health problem. In context to Nepal, the prevalence of HBV infection is found to be low, 0.9% (1.1% in males and 0.5% in females), though high prevalence of ≥8% is shown among the population in the mountainous region by several studies. The epidemiology of HBV infection in the population of Jumla is not well-known. This study aimed to find out the seroprevalence of HBV surface antigen (HBsAg) in patients visiting Karnali Academy of Health Sciences Teaching Hospital (KAHS-TH), Jumla, Nepal.

Methods: The cross-sectional study was conducted in people visiting KAHS-TH, Jumla for testing HBsAg from 1st April 2018 to 31st March 2019. The samples collected were tested for HBsAg by using the Rapid HBsAg test kit. All positive cases were further tested by Chemiluminescence (CLIA) method for HBsAg. The data entry was done in Microsoft Excel. After transferring the data into SPSS version 16, data analysis was done.

Results: In this study, 1704 individuals were screened during the study period, out of which, 53 (3.11%) were HBsAg positive.  Among the HBsAg positive cases, 22 (4.34%) were males and 31 (2.58%) were females. The highest prevalence (8.1%) was observed in the age group of 40– 45 years. But the prevalence rate is zero in 0-5 years age group and above 65 years of age.

Conclusion: The HBV infection was higher in Jumla as compared to an overall prevalence of Nepal. Males were more infected than females and the middle age group were at the high-risk group of HBV infection.

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Published

2020-12-04

How to Cite

1.
Pun Magar B, Thapa N, Rana E, Joshi KR, Tiwari AP. Seroprevalence of Hepatitis B Virus Surface Antigen (HBsAg) Positivity in KAHS Teaching Hospital, Jumla. Journal of Karnali Academy of Health Sciences [Internet]. 2020Dec.4 [cited 2024Apr.20];3(2):128-33. Available from: https://jkahs.org.np/jkahs/index.php/jkahs/article/view/291

Issue

Vol. 3 No. 2 (2020): JKAHS; May-Aug Issue (8)

Section

Original Article

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