A Comparative study of Extra-Amniotic Saline Infusion (EASI), Foley’s Catheter and Prostaglandin E2(PGE2) gel for Pre-Induction Cervical Ripening

Authors

  • K Dhakal Department of Gynecology & Obstetrics, Mid-Western Regional Hospital. Surkhet.
  • S Dhakal Rai Faculty of Health ad social sciences, Bournmouth University, United Kingdom.

Abstract

Introduction: Cervical ripening is essential for successful induction of labor. The aim of the study is to compare the efficacy, safety and cost-effectiveness of extra-amniotic saline infusion, Foley’s catheter and intra-cervical PGE2 gel for pre-induction cervical ripening.

Methods: A total 150 women having indications of labor induction were randomly assigned equally into three groups: EASI, Foley’s catheter and PGE2 gel. Eligible full-term pregnancy with Bishop score 4 or less was recruited for the study. Computer generated randomization method and random numbers were used to allocate cases into three groups. Data were analyzed by SPSS. The induction to cervical ripening interval, induction to delivery time, changes in the Bishop Score, mode of delivery and cost were assessed.

Results: Majority of the cases was primigravida (67.3%) and the most common indication of induction was postdated pregnancy (72%). The mean time for induction to cervical ripening interval was shorter in Foley’s catheter and EASI than PGE2 (6.92 & 5.69 vs 11.08 (P<0.006). Majority of cases in Foley’s catheter and EASI achieved the Bishop score of 7 or more within 24 hours of induction as compared to PGE2 (88% & 84% vs 54%, P<0.000). The mean induction to delivery time is found shorter in EASI and Foley’s catheter than PGE2 (14.95hrs &16.84hrs vs 23.18hrs).

Conclusion: Foley’s catheter and extra-amniotic saline infusion (EASI) are the most efficacious, cost effective and safe methods of cervical ripening as compared to PGE2 gel.

Keywords: Cervical ripening, induction of labor, EASI, PGE2,Foley’s catheter.

Downloads

Published

2018-10-06

How to Cite

1.
Dhakal K, Rai SD. A Comparative study of Extra-Amniotic Saline Infusion (EASI), Foley’s Catheter and Prostaglandin E2(PGE2) gel for Pre-Induction Cervical Ripening. Journal of Karnali Academy of Health Sciences [Internet]. 2018Oct.6 [cited 2024Apr.24];1(02):28-32. Available from: https://jkahs.org.np/jkahs/index.php/jkahs/article/view/8

Issue

Vol. 1 No. 02 (2018): JKAHS; May-Aug Issue (2)

Section

Original Article

License

The author(s) retain the copyright and the full publishing right without restriction under the Creative Commons Attribution 4.0 International License (CC BY 4.0) which allows readers to share (copy and redistribute the material in any medium or format) and adapt (remix, transform, and build upon the material) for any purpose, even commercially, provided the work is properly attributed. (https://creativecommons.org/licenses/by/4.0/).

Author(s) grant the non-exclusive publishing right to the Journal of Karnali Academy of Health Sciences (JKAHS). The publishing rights include the rights to publish, reproduce, distribute, include in indexes or search databases or other media in print or online. The JKAHS may require revisions to the manuscript before acceptance for publication or may choose not to publish it based on the judgement of the editors. Further, JKAHS might retract, withdraw, or publish a correction or other notice after publication, if such publication would be inconsistent with the good publication practices and associated guidelines set forth by the COPE (Committee on Publication Ethics) (https://publicationethics.org/core-practices).

More information about the Creative Commons Attribution 4.0 International License can be found in the webpage of Creative Commons (CC) by following the link provided below:  https://creativecommons.org/licenses/by/4.0/