Morphometric Variations of Thyroid Gland: A Cadaveric Study

Authors

  • Laxmi Bhattarai Lecturer, Universal College of Medical Science, Bhairahawa, Nepal

DOI:

https://doi.org/10.61814/jkahs.v6i2.673

Keywords:

Isthmus, Levator glandulae thyroidea, Morphology, Pyramidal lobe

Abstract

Background: The size of thyroid gland is subject to great variations. The thyroid gland consists of two lobes and a bridging isthmus. It is located anteriorly in the neck at the level of the C5–T1 vertebrae deep to the Infrahyoid muscles. The developmental anomalies of the thyroid gland are partial and total agenesis, various ectopic tissues, accessory thyroid, and absence of isthmus. This distorts the morphology of the gland and causes clinical and functional disorders.

Methods: The thyroid gland was removed from 28 embalmed cadavers. Specimen of abnormal conditions like enlarged gland, partial and total agenesis of gland and absent isthmus was excluded from the study. Presence of pyramidal lobe and levator glandulae thyroidea was noted. The dimensions of each lobe was measured using Vernier caliper. Descriptive statistics was calculated as mean and standard deviation.

Results: The average length (right lobe=4.96cm, left lobe= 4.48cm), width (right lobe=2.25cm, left lobe=1.86cm) and thickness (right lobe=1.53cm, left lobe=1.45cm) were measured. Pyramidal lobe was present in 32.14%. Levator glandulae thyroidea was found in only one case (3.57%).

Conclusion: Variation in the dimensions of thyroid gland are reported. Knowledge of the wide ranging variations and measurements will help the surgeons and radiologists in correct interpretation, diagnosis and treatment of thyroid diseases.

Author Biography

Laxmi Bhattarai, Lecturer, Universal College of Medical Science, Bhairahawa, Nepal

Lecturer, Universal College of Medical Science, Bhairahawa, Nepal

References

Sgalitzer KE. Contribution to the study of the morphogenesis of the thyroid gland. Journal of anatomy. 1941 Jul;75(Pt 4):389. [PMID: 17104869] [PubMed] [Google Scholar] [Full Text]

Saddler, T. W. "Langman’s Medical Embryology. Thyroid Gland." 11th Ed. Lippincott Williams and Wilkins. 2010;278. ISBN: 0781790697

Rajkonwar AJ, Kusre G. Morphological variations of the thyroid gland among the people of upper Assam region of northeast India: a cadaveric study. Journal of clinical and diagnostic research: y. J Clin Diagn Res. 2016 Dec;10(12):01-3. [Pub Med] [DOI] [Google Scholar] [Full Text]

Hegedüs L, et al. The determination of thyroid volume by ultrasound and its relationship to body weight, age, and sex in normal subjects. The Journal of Clinical Endocrinology & Metabolism. 1983 Feb 1;56(2):260-3. [PubMed] [DOI] [Google Scholar]

Ying M, Yung DM. Asymmetry of thyroid lobe volume in normal Chinese subjects: association with handedness and position of esophagus. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology: Advances in Integrative Anatomy and Evolutionary Biology. 2009 Feb;292(2):169-174. [PubMed] [DOI] [Google Scholar] [Full Text]

Raut RS, Jadhav SS, Kulkarni PR. Morphometric study of pyramidal lobe and levator glandulae thyroidae and its surgical significance. International Journal of Anatomy and Research. 2018;6(3.2):5538-43.[DOI] [Google Scholar] [Full Text]

Braun EM, Windisch G, Wolf G, Hausleitner L, Anderhuber F. The pyramidal lobe: Clinical anatomy and its importance in thyroid surgery. Surgical and radiologic anatomy. 2007 Feb;29(1):21-7. [PubMed] [DOI] [Google Scholar]

Marshall CF. Variations in the form of the thyroid gland in man. Journal of anatomy and physiology. 1895 Jan;29( 2):234-9. [PubMed] [Google Scholar] [Full Text]

Cunningham’s Manual of practical Anatomy.16th Ed:Vol 3, Head and Neck and Brain. 2018;51-5. ISBN: 0198749384,9780198749387.

Joshi SD, Joshi SS, Daimi SR, Athavale SA. The thyroid gland and its variations: A cadaveric study. Folia Morphol (Warsz). 2010 Feb;69(1):47-50. [PubMed] [Google Scholar] [Full Text]

Blumberg NA. Observations on the pyramidal lobe of the thyroid gland. South African Medical Journal. 1981 Jun 20;59(26):949-50. [PubMed] [Google Scholar]

Prakash, et al. Variations in the anatomy of the thyroid gland: clinical implications of a cadaver study. Anatomical science international. 2012 Mar;87:45-9. [DOI] [Google Scholar] [PubMed]

Tanriover O, et al. Morphometric features of the thyroid gland: a cadaveric study of Turkish people. Folia morphologica. 2011 May;70(2):103-8. [PubMed] [Google Scholar] [Full Text]

Diana SM, Subramanian RK, Senthil S. Morphometric features of thyroid gland: A detailed cadaveric study. International Journal of Anatomy and Research. 2016;2(9):856-9. [Full Text]

Al-Azzawi A, Takahashi T. Anatomical variations of the thyroid gland: An experimental cadaveric study. Annals of Medicine and Surgery. 2021 Sep 8;70:102823 [DOI].[PubMed] [Google Scholar] [Full Text]

Ranade AV, et al. Anatomical variations of the thyroid gland: possible surgical implications. Singapore medical journal. 2008 Oct 1;49(10):831. [PubMed] [Google Scholar] [Full Text]

M B Saknure, C S Halnikar (Waghmare). Morphological variation of thyroid gland in cadavers. MedPulse International Journal of Anatomy. 2017 July;3(1):08-11. [DOI][Full Text]

Hoang JK, Branstetter IV BF, Gafton AR, Lee WK, Glastonbury CM. Imaging of thyroid carcinoma with CT and MRI: approaches to common scenarios. Cancer Imaging. 2013 March;13(1):128. [DOI] [PubMed] [Google Scholar] [Full Text]

Reddy CK, Panchakshari M. A study of anatomical and morphological variations of the thyroid gland. Journal of Clinical and Diagnostic Research. 2016 Sep;4:3510-13. [Google Scholar] [Full Text]

Harjeet A, Sahni D, Jit I, Aggarwal AK. Shape, measurements and weight of the thyroid gland in northwest Indians. Surgical and radiologic anatomy. 2004 Apr 1;26(2):91-5.[DOI] [PubMed] [Google Scholar] [Full Text]

Taty-Anna K, Farihah HS, Norzana AG, Farida H, Das S. Absence of the isthmus of the thyroid gland: anatomical and clinical considerations. La Clinica therapeutica. 2012 Nov;163(6):503-4 .[PubMed] [Google Scholar] [Full Text]

Larochelle D, Arcand P, Belzile M, Gagnon NB. Ectopic thyroid tissue--a review of the literature. The Journal of otolaryngology. 1979 Dec 1;8(6):523-30. [PubMed] [Google Scholar]

Patra A, Sharma A, Malhotra V, Gupta V. Morphological Variations of the Thyroid Gland in the North Indians: A Cadaveric Study with its Clinical Relevance. Academia Anatomica International. 2019;5(1):43-8. [DOI] [Google Scholar] [Full Text]

Published

2023-08-31

How to Cite

1.
Bhattarai L. Morphometric Variations of Thyroid Gland: A Cadaveric Study: . Journal of Karnali Academy of Health Sciences [Internet]. 2023Aug.31 [cited 2024May14];6(2). Available from: https://jkahs.org.np/jkahs/index.php/jkahs/article/view/673

Similar Articles

You may also start an advanced similarity search for this article.